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confirmed that overexpressed SLC1A3 in gastric cancer activates the PI3K/AKT pathway, upregulates the expression levels of Glucose transporter 1 (GLUT1), Hexokinase 2 (HK2), and Lactate dehydrogenase A (LDHA), and promotes the growth of gastric cancer, while treatment with the PI3K/AKT inhibitor LY294002 could inhibit the growth-promoting effect of SLC1A3 overexpression on gastric cancer

In some cases, gallstones cause chronic inflammation in the gallbladder ( chronic cholecystitis ), leading to thickening of the gallbladder walls (Jones, Ferguson 2018)

A., Burlacu, A

Ophthalmic Res

Additionally, patients receiving treatments affecting bone marrow function need careful monitoring during therapy